Wyoming Highway 331 is a 9.92-mile (16.0 km) east-west Wyoming State Road located in central Sheridan County and links Beckton with Sheridan.

Wyoming Highway 331 starts its western end in the community of Beckton, west of sheridan, at Sheridan County Route 53 (Big Goose Canyon Road). WYO 331 heads east continuing the name Big Goose Canyon Road toward Sheridan as it paralles Big Goose Creek to the north. As WYO 331 reaches the outer limits of Sheridan, it changes to into W. Loucks Street and crosses over Big Goose Creek. WYO 331 comes to an end at I-90 Business/US 14 Business/US 87 Business (N. Main Street) after almost 10 miles.

The entire route is in Sheridan County.