State Route 19 (SR 19) is a state highway that runs southeast-to-northwest through portions of Bacon, Jeff Davis, Appling, Telfair, Wheeler, Laurens, Twiggs, Bibb, and Monroe counties in central Georgia. The route runs from its southern terminus at US 1, US 23, and SR 4 north of Alma to its northern terminus at US 41 and SR 18 in Forsyth.

From its southern terminus at U.S. Route 1/State Route 4 (US 1/SR 4) north of Alma, the route travels north, concurrent with US 23. In Hazlehurst, US 341 and SR 27, also join the two routes. In Lumber City, SR 19 departs to the north, crossing the Little Ocmulgee River, and begins to parallel the Oconee River north to Dublin. In Dublin, SR 19 runs concurrent with US 80. The two routes travel west to Macon. In Macon, SR 19 leaves US 80 and runs concurrent with US 41. The routes travel north to Forsyth, where SR 18 runs concurrent with US 41 and SR 19 reaches its northern terminus.

In 1998, the Georgia state legislature passed a resolution designating a portion of State Highway 19 in Macon as "Duane Allman Boulevard" and a bridge thereon as "Raymond Berry Oakley III Bridge" in honor and remembrance of late founding members of The Allman Brothers Band.

State Route 19 has one banner route, State Route 19 Connector (SR 19 CONN). This short route is located entirely in Jeff Davis County.