San Simon, Arizona is close to the interstate highway I-10. It is neighboring other cities: Rodeo, NM (19.8mi/42m ); Animas, NM (34.4mi/1.1h ); Bowie, AZ (35.3mi/1.1h ). You can get to the city from exit 382 of i10 (33.9mi/1h ); exit 390 of i10 (25.6mi/53m ); exit 378 of i10 (21mi/48m ). San Simon, Arizona can reach interstate highways: i10 (33.9mi/1h ); i19 (140.5mi/2.9h ); i25 (166.8mi/3.8h ). It is also close to local highways: NM 80 (27.8mi/52m ); AZ 181 (26.4mi/1.1h ); NM 9 (23.9mi/47m ).