Mesilla Park, New Mexico is close to the interstate highway I-25. It is neighboring other cities: La Mesa, NM (7.11 mi ); Las Cruces, NM (8.10 mi ); Mesquite, NM (8.73 mi ). You can get to the city from exit 144 of i10 (4.76 mi ); exit 151 of i10 (6.41 mi ); exit 142 of i10 (8.12 mi ). Mesilla Park, New Mexico can reach interstate highways: i10 (4.76 mi ); i25 (8.75 mi ); i20 (282.11 mi ). It is also close to local highways: NM 478 (0.65 mi ); NM 28 (3.67 mi ); US 180 NM (4.82 mi ).