Pueblo, Colorado is close to the interstate highway I-25. It is neighboring other cities: Wild Horse, CO (7.4mi/14m ); Avondale, CO (13.9mi/18m ); Boone, CO (19.8mi/25m ). You can get to the city from exit 99b a of i25 (2.9mi/5m ); exit 98b of i25 (3.3mi/5m ); exit 100a of i25 (3.5mi/6m ). Pueblo, Colorado can reach interstate highways: i25 (2.9mi/5m ); i70 (115.2mi/2.3h ); i225co (102.1mi/1.8h ). It is also close to local highways: US 50 CO (0.2mi/0m ); CO 96 (1.1mi/3m ); CO 47 (1.7mi/3m ).