Charleston, South Carolina is close to the interstate highway I-26. It is neighboring other cities: Chesterfield, SC (5.6mi/11m ); Mount Pleasant, SC (7.1mi/14m ); North Charleston, SC (6.5mi/10m ). You can get to the city from exit 221 of i26 (2.1mi/5m ); exit 221b of i26 (2.4mi/6m ); exit 221a of i26 (3.3mi/7m ). Charleston, South Carolina can reach interstate highways: i26 (2.1mi/5m ); i526sc (7.7mi/14m ); i95 (54.1mi/1.3h ). It is also close to local highways: SC 30 (1.5mi/5m ); US 17 SC (1.8mi/5m ); US 78 SC (1.7mi/4m ).