Middlesex, New Jersey is close to the interstate highway I-295 NJ. It is neighboring other cities: Dunellen, NJ (2.3mi/6m ); Bound Brook, NJ (2.3mi/6m ); South Bound Brook, NJ (2.6mi/7m ). You can get to the city from exit 8 of i287nj (1.9mi/5m ); exit 9 of i287nj (3.4mi/8m ); exit 7 of i287nj (3.8mi/8m ). Middlesex, New Jersey can reach interstate highways: i287nj (1.9mi/5m ); i78 (6.9mi/16m ); i95 (10.5mi/17m ). It is also close to local highways: NJ 28 (0.5mi/2m ); NJ MIDDLESEX 607 (0.7mi/3m ); NJ SOMERSET 634 (1mi/4m ).