Roanoke, Virginia is close to the interstate highway I-81. It is neighboring other cities: Pleasant Valley, VA (2.1mi/5m ); Cedar Bluff, VA (2mi/5m ); Colonial Heights, VA (2.7mi/6m ). You can get to the city from exit 143 of i81 (9.5mi/17m ); exit 141 of i81 (6.8mi/14m ); exit 140 of i81 (11.7mi/25m ). Roanoke, Virginia can reach interstate highways: i81 (9.5mi/17m ); i64 (55.8mi/1.4h ); i77 (69.5mi/1.4h ). It is also close to local highways: US 11 VA (0.3mi/1m ); US 221 VA (0.6mi/2m ); VA 116 (1.4mi/3m ).