Wise, North Carolina is close to the interstate highway I-85. It is neighboring other cities: Warrenton, NC (3.4mi/6m ); Macon, NC (7.2mi/11m ); Snow Hill, NC (5.9mi/12m ). You can get to the city from exit 229 of i85 (15mi/25m ); exit 226 of i85 (12.2mi/22m ); exit 223 of i85 (19.6mi/30m ). Wise, North Carolina can reach interstate highways: i85 (15mi/25m ); i95 (27.7mi/49m ); i440nc (55.5mi/1.4h ). It is also close to local highways: NC 58 (0.1mi/1m ); NC 43 (1.6mi/3m ); US 401 NC (3.7mi/7m ).