Live Chat I-85 Community Nearby Traffic US 221 SC 2024-04-25 Roadnow Weather | Gas | Restaurants | Hotels | Car Repair | Convenience Stores Cities close to US 221 SC Spartanburg, SC 4.74 Clifton, SC 7.15 Converse, SC 7.65 Interstate highway exits close to US 221 SC Exit 77, i85 4.83 Exit 78, i85 5.57 Exit 75, i85 6.80 Interstate highways close to US 221 SC i85 map 4.83 i26 map 8.92 i385sc map 38.69 State roads close to US 221 SC US 29 SC map 0.78 SC 9 map 1.92 SC 296 map 1.92