Hopkinton, Massachusetts is close to the interstate highway I-90. It is neighboring other cities: Woodville, MA (2.4mi/4m ); Ashland, MA (4.9mi/8m ); Upton, MA (4.9mi/10m ). You can get to the city from exit 21b a of i495ma (1.2mi/2m ); exit 22 of i495ma (4.9mi/7m ); exit 11a of i90 (13.2mi/22m ). Hopkinton, Massachusetts can reach interstate highways: i495ma (1.2mi/2m ); i90 (13.2mi/22m ); i290ma (13.7mi/17m ). It is also close to local highways: MA 135 (4.3mi/7m ); MA 140 (5.3mi/10m ); MA 9 (6.9mi/9m ).