Walterboro, South Carolina is close to the interstate highway I-95. It is neighboring other cities: Round O, SC (8.7mi/14m ); Gloverville, SC (13.5mi/26m ); Ruffin, SC (15.8mi/28m ). You can get to the city from exit 57 of i95 (3.2mi/7m ); exit 53 of i95 (7.1mi/11m ); exit 62 of i95 (20mi/26m ). Walterboro, South Carolina can reach interstate highways: i95 (3.2mi/7m ); i26 (39.3mi/46m ); i526sc (43.8mi/1.1h ). It is also close to local highways: SC 63 (0.2mi/1m ); SC 303 (0.2mi/1m ); US 15 SC (0.6mi/1m ).