Bluffton, South Carolina is close to the interstate highway I-95. It is neighboring other cities: Hilton Head Island, SC (14.5mi/28m ); Green Pond, SC (24.3mi/34m ); Hardeeville, SC (14.5mi/27m ). You can get to the city from exit 8 of i95 (16.3mi/23m ); exit 5 of i95 (37.6mi/48m ); exit 18 of i95 (31.4mi/41m ). Bluffton, South Carolina can reach interstate highways: i95 (16.3mi/23m ); i16 (23mi/39m ); i526sc (87.3mi/1.9h ). It is also close to local highways: SC 46 (0.4mi/2m ); US 278 SC (2.7mi/6m ); SC 170 (9.9mi/17m ).