Darlington, South Carolina is close to the interstate highway I-95. It is neighboring other cities: Hickory Grove, SC (8.6mi/19m ); Florence, SC (10.8mi/18m ); Timmonsville, SC (13.1mi/25m ). You can get to the city from exit 164 of i95 (8.8mi/16m ); exit 137 of i20 (14.6mi/24m ); exit 141b a of i20 (10.5mi/19m ). Darlington, South Carolina can reach interstate highways: i95 (8.8mi/16m ); i20 (14.6mi/24m ); i77 (67.8mi/1.4h ). It is also close to local highways: SC 340 (0.6mi/2m ); US 52 SC (0.8mi/2m ); SC 34 (0.7mi/2m ).