Live Chat I-95 Community Nearby Traffic US 21 SC 2024-05-31 Roadnow Weather | Gas | Restaurants | Hotels | Car Repair | Convenience Stores Cities close to US 21 SC Beaufort, SC 6.03 Hilton Head Island, SC 10.62 Port Royal, SC 13.19 Interstate highway exits close to US 21 SC Exit 21, i95 41.27 Exit 22, i95 42.10 Exit 33, i95 42.40 Interstate highways close to US 21 SC i95 map 41.27 i16 map 61.53 i526sc map 67.31 State roads close to US 21 SC US 21 SC map 3.09 SC 802 map 10.38 SC 281 map 12.99