Live Chat I-95 Community Nearby Traffic US 21 SC 2024-06-10 Roadnow Weather | Gas | Restaurants | Hotels | Car Repair | Convenience Stores Cities close to US 21 SC Saint Helena Island, SC 6.03 Hilton Head Island, SC 9.74 Port Royal, SC 12.62 Interstate highway exits close to US 21 SC Exit 33, i95 37.53 Exit 28, i95 38.39 Exit 21, i95 38.58 Interstate highways close to US 21 SC i95 map 37.53 i16 map 63.75 i526sc map 64.47 State roads close to US 21 SC US 21 SC map 2.71 SC 802 map 6.80 SC 281 map 11.39