Live Chat I-95 Community Nearby Traffic US 21 (SC) 2024-04-26 Roadnow Weather | Gas | Restaurants | Hotels | Car Repair | Convenience Stores Cities close to US 21 (SC) Sheldon, SC 10.59 Early Branch, SC 12.06 Seabrook, SC 14.96 Interstate highway exits close to US 21 (SC) Exit 38, i95 4.36 Exit 33, i95 7.28 Exit 42, i95 7.77 Interstate highways close to US 21 (SC) i95 map 4.36 i26 map 70.46 i16 map 72.18 State roads close to US 21 (SC) SC 68 map 1.89 US 21 SC map 1.91 US 17 SC map 4.86