State Route 183 or SR-183 is a 47.443-mile (76.352 km) state highway that serves as a north-south connection predominantly through Perry County. SR-185 intersects US-80 at its southern terminus in Uniontown and US-82 at its northern terminus in Chilton County.

State Route 183 begins at its intersection with US-80 in Uniontown. From this point, the route travels in a northerly direction through Uniontown before taking a more northeasterly course in route to Marion. At Marion, SR-183 begins an approximately 4-mile (6.4 km) concurrency with SR-5 through the town and then begins another approximately 4-mile (6.4 km) concurrency SR-14 at the eastern end of Marion through Sprott. From Sprott, SR-183 continues on its northeasterly course through the Talladega National Forest in route to its northern terminus at US-82 in Chilton County.