State Route 263 or SR-263 is a 15-mile (24 km) long route that serves as a connection between State Route 185 northwest of Greenville with State Route 21 at Braggs.

The northern terminus of SR-263 is located at its intersection with State Route 21 in Braggs. The route then takes a southeasterly track to its southern terminus at State Route 185 in Fort Dale to the northwest of Greenville.