State Route 157 (SR 157) is a highway that runs north-to-south through portions of Dade, Walker, and Chattooga counties in northwestern Georgia. The route runs from its northern terminus at its connection with SR 148 across the Tennessee state line near Lookout Mountain to its southern terminus at SR 48 and SR 117 northwest of Menlo.

The route is co-signed with SR 189 for 4.6 miles (7.4 km) from the Tennessee state line. It runs parallel to I-59 for all of its length.