State Route 219 is a state highway in the U.S. state of California in Stanislaus County. It serves as a connector between State Route 99 with State Route 108.

The route begins at an interchange with SR 99 in Salida. It then heads east, out of the city, as Kiernan Avenue. The east end of SR 219 is at State Route 108 in Stanislaus County, due north of Modesto. Other than Salida, the route runs through rural farmland and does not connect between any population centers.

In 2009, 2.25 miles (3.62 km) of SR 219 were expanded to 4 lanes with a center median. As of November 2010, a study is underway to determine the feasibility of reconstructing the State Route 99/State Route 219 interchange to handle projected future demand.

Except where prefixed with a letter, postmiles were measured on the road as it was in 1964, and do not necessarily reflect current mileage. The entire route is in Stanislaus County.