Live Chat AI Agent Community US 221 SC 2024-07-04 Roadnow click anywhere on map to find more poi nearby Weather | Gas | Restaurants | Hotels | Car Repair | Convenience Stores Cities close to US 221 SC Cross Hill, SC 10.74 Waterloo, SC 10.92 Clinton, SC 13.37 Interstate highway exits close to US 221 SC Exit 2, i385sc 18.17 Exit 52, i26 18.86 Exit 54, i26 18.87 Interstate highways close to US 221 SC i385sc map 18.17 i26 map 18.86 i85 map 59.48 State roads close to US 221 SC SC 72 map 1.02 SC 39 map 1.49 SC 560 map 6.56