State Route 338 (SR 338) is a north–south state highway completely in Laurens County in central Georgia.

SR 338 begins at an intersection with SR 117 in Cadwell, while the roadway continues south as Old Eastman Road. The route continues north, passing through the town of Dexter, where it has a concurrency with SR 257. The route continues to travel north, then turns northeast, to an interchange with Interstate 16 southwest of Dudley. In Dudley, SR 338 intersects US 80/SR 19/SR 26. The route continues to its northern terminus at US 441/SR 29 northwest of Dublin, while the roadway continues northeast as Holly Ridge Road.

The entire route is in Laurens County.