NC 191 is a north-south state highway in western North Carolina in northern Henderson and central Buncombe County.

North Carolina Highway 191 begins its southern end at US Route 25 (Asheville Highway) in the city of Hendersonville in Henderson County. NC 191 travels northwest from Hendersonville and enters the town of Mills River where it meets North Carolina Highway 280. NC 191 joins NC 280 northward for a short distance before separating after approximately a mile. Highway 191 continues north towards Asheville, leaving Henderson County and entering Buncombe County before meeting the western terminus of North Carolina Highway 146 (Long Shoals Road) in the community of Avery Creek. Past Avery Creek, Highway 191 intersects the scenic Blue Ridge Parkway, a National Parkway and All-American Road. NC 191 continues north into Venable, intersecting the eastern terminus of North Carolina Highway 112 (Sardis Road) and then I-26/US 74 at exit 33 respectively as it reaches the outer limits of Asheville. Entering Asheville, NC 191 interchanges with Interstate 40 (exit 47) and half a mile later I-26/I-240 (exit 1b). NC 191 heads into the southwestern section of Asheville named Brevard Road. At just over 21.5 miles, NC 191 reaches its northern end at US 19 BUS/US 23 BUS (Haywood Road).

North Carolina Highway 191 is an original state highway. In 1971, Highway 191 was routed along modern-day I-240 from Brevard Road to Haywood Road, a highway that was previously unnumbered. As a result, Brevard Road became unnumbered north of the freeway. Around 1981, NC 191 was moved back onto Brevard Road to end where it currently does at US 19 BUS/US 23 BUS. The freeway became I-240.