North Carolina Highway 116 is a primary state highway in the state of North Carolina. The highway runs east–west but is signed south–north, connecting the town of Webster between two major highways in Jackson County.

NC 116 is a two-lane mountain valley highway; it is best known as a short-cut to Western Carolina University from Franklin and North Georgia. Mildly curvy, it passes through the town of Webster, where it crosses the Tuckasegee River.

Established in 1930 as new primary routing from NC 285 (today as Old Franklin Road) to NC 106 (renumbered in 1940 as NC 107). In the mid-1950s, the highway was extended west to a new alignment of US 23/US 441.

The entire route is in Jackson County.