Highway 357 (AR 357, Ark. 357, and Hwy. 357) is a north–south state highway in St. Francis County, Arkansas. The route of 9.20 miles (14.81 km) runs from Highway 50 north to US 70.

Highway 357 begins at Highway 50 near Greasy Corner and runs north through many unincorporated communities. The route passes through Davis, Stump City, Jonquil and Willow Bend. Further north the route intersects US 70 and terminates. US 70 is essentially a frontage road to Interstate 40.

The entire route is in St. Francis County.