State Route 250 is a secondary state highway which runs from just north of White Bluff on State Route 47 in eastern Dickson County to State Route 49 just west of Ashland City. It runs through the rural communities of Claylick, Petway, and Griffintown, and through the Cheatham State Wildlife Management Area. Between White Bluff and Claylick, it is locally known as Claylick Road, and between Claylick and Petway as Petway Road.