South Dakota Highway 324 is a short highway linking State Highway 13 east of Elkton to Interstate 29 just south of Brookings. It was commissioned in 1997, along what was formerly named State Highway 218, which itself followed an old routing of U.S. Route 14.

Highway 324 travels east as 217th Street, intersecting both County Road 21 and County Road 23. The highway ends after a few miles at Highway 13.

The entire route is in Brookings County.