State Highway 116 is a fairly isolated state highway that runs from the Kansas state line (W Road 12) in the southeastern corner of the state.

The highway gives service though very rural country in Baca County through Two Buttes to the junction with US 287 and US 385 about 7 miles north of Springfield. The highway's maintenance is served by Two Buttes, the only town on its route. The town is the largest town for many miles in any direction.

The entire route is located in Baca County.