Route 571 is a two-lane highway in Carthage, Missouri replacing a former section of U.S. Route 71 Alternate with the realignment of U.S. Route 71. Both termini are at Interstate 49 and US 71; its northern terminus is Business US 71 & Route 171 at the western edge of Carthage and its southern terminus is US 71 at the southern edge of Carthage.

Route 571 begins at a fork from the right-of-way of Interstate 49 and U.S. Route 71 (Trooper Charles P. Corbin Memorial Highway) southbound. The designation follows South Grand Avenue, a commercial strip into a roundabout with Airport Drive before continuing south as Fairlawn Avenue. After a stint to the northeast, the designation changes once again to South Garrison Avenue. This commercial strip is interrupted by another short stint at the intersection with West Centennial Avenue, paralleling the nearby freight railroad tracks. At the intersection with West Central Avenue (Route 96), Route 571 turns westward along West Central from South Garrison, creating a concurrency. The two highways create a commercial strip down West Central, crossing under the railroad near North Parsons Street. Route 571 terminates at an interchange with U.S. Route 71 (Trooper Charles P. Corbin Memorial Highway) in Carthage, Missouri, which also serves as the eastern termini for Interstate 49 Business and Route 171. Route 96, which is concurrent with Route 171 and U.S. Route 71 Business, continues eastward along West Central Avenue.

The entire route is in Carthage, Jasper County.