Wyoming Highway 332 is a 5.44-mile (8.8 km) north-south Wyoming State Road in central Sheridan County.

Wyoming Highway 332 begins its southern end just south of Sheridan at an intersection with U.S. Route 87 and the northern terminus of Wyoming Highway 335. WYO 332 heads north, named Big Horn Avenue, and roughly parallels US 87 on it way into Sheridan. Passing east of the Sheridan County Airport, WYO 332 intersects the western terminus of Wyoming Highway 334 (E. Brundage Ln.) at 3.8 miles before intersecting the eastern terminus of Wyoming Highway 333 (Airport Rd.) at just over 4 miles which provides access to the airport. One mile north, WYO 332 turns east for one block onto W. College Avenue and then turns north onto S. Main Street to finish its routing. Highway 332 reaches its northern terminus at an intersection with I-90 BUS/US 14 BUS/US 87 BUS.

The entire route is in Sheridan County.