Minnesota State Highway 149 is a highway in Minnesota that runs from its intersection with State Highway 3 in Inver Grove Heights to its northern terminus at its intersection with State Highway 5 (W. 7th Street) in Saint Paul. The route is 10 miles (16 km) in length.

Outside of the Saint Paul city limits, Highway 149 is known as Dodd Road. 149 is known as Smith Avenue within Saint Paul and passes over the Smith Avenue High Bridge crossing the Mississippi River.

Highway 149 serves as a north–south route between the communities of Eagan, Mendota Heights, West St. Paul, and the "West Side" neighborhood of Saint Paul. The northern terminus of the route is at W. 7th Street / Fort Road near downtown Saint Paul.

Highway 149 was marked in 1981.

The route was originally authorized in 1920 as Trunk Highway 1. It was later part of U.S. Route 65 from 1927 to 1934.

The route was paved (as 65) by 1929.

In 1934, this route was renumbered State Highway 88 when U.S. 65 was rerouted on a different alignment.

The route was renumbered again in 1950 as an extension of State Highway 49.

By 1981, the route was renumbered 149 when a portion of State Highway 49 through downtown Saint Paul was turned back to local maintenance.

The Smith Avenue High Bridge over the Mississippi River was originally a steel truss bridge built around 1895 and rebuilt as a concrete arch in 1987.

Before it was a numbered highway in the 1920s, Dodd Road was a historic route in Minnesota. It was originally built in 1853 by Minnesota pioneer William B. Dodd and his crew. The road was built as a connection between the city of Mendota and the city of St. Peter (in south-central Minnesota) to help the development of St. Peter during its frontier days. Dodd Road was financed using private funds at a time when most roads were financed by the government to aid settlers. Present day Highway 149 bears little resemblance to the frontier road.