Wyoming Highway 254 is a 4.06-mile (6.53 km) state road northwest of Casper, Wyoming known as Salt Creek Highway.
Wyoming Highway 254 begins its south end the Town of Mills, just outside Casper at US 20 Business/US 26 Business (Yellowstone Highway). The Highway continues north into the Town of Bar Nunn at 0.79 miles (located northwest of Casper). Highway 254 intersects US 20/US 26 (Casper Bypass) at 1.40 miles (2.25 km). WYO 254 continues north until 3.9 miles (6.3 km) where it turns east onto Wardwell Road for a short distance and there meets I-25/US 87 (exit 191) where WYO 254 ends.
WYoming Highway 254 is the former alignment of US 87 prior to relocation along I-25.
The entire route is in Natrona County.