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Interstate 385 Travel Guide

Interstate 385 (I-385) is an Interstate Highway located in The Upstate region of South Carolina. It goes from Clinton, South Carolina at Interstate 26 to Greenville, South Carolina at Laurens Road/U.S. 276 (Exit 42). After exit 42, Interstate 385 turns into a Business Spur and becomes East North Street and later — for northbound motorists only — Beattie Place. The ... more.


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