Wentzville, Missouri is close to the interstate highway I-70. It is neighboring other cities: Lake Saint Louis, MO (6.56 mi ); Foristell, MO (7.41 mi ); New Melle, MO (10.40 mi ). You can get to the city from exit 209 of i70 (0.53 mi ); exit 208 of i70 (1.35 mi ); exit 210b a of i70 (1.76 mi ). Wentzville, Missouri can reach interstate highways: i70 (0.53 mi ); i64 (21.89 mi ); i44 (36.32 mi ). It is also close to local highways: US 40 MO (1.39 mi ); US 61 MO (1.57 mi ); MO 79 (13.80 mi ).