Wentzville, Missouri is close to the interstate highway I-70. It is neighboring other cities: Lake Saint Louis, MO (4.8mi/10m ); Foristell, MO (6.5mi/10m ); New Melle, MO (8.1mi/14m ). You can get to the city from exit 209 of i70 (0.7mi/3m ); exit 208 of i70 (2mi/4m ); exit 210b a of i70 (1.6mi/4m ). Wentzville, Missouri can reach interstate highways: i70 (0.7mi/3m ); i64 (17.1mi/24m ); i44 (40.9mi/58m ). It is also close to local highways: US 40 MO (1.5mi/4m ); US 61 MO (2.4mi/6m ); MO 79 (14.3mi/22m ).