SC Highway 381 Travel Info
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South Carolina Highway 381 (SC 381) is a primary state highway in the U.S. state of South Carolina. It connects the towns in eastern Marlboro County.
SC 381 traverses 22.5 miles (36.2 km), from Blenheim, to the North Carolina state line. As a two-lane rural highway, it connects the towns of Clio and McColl.
Established in 1930 as a new primary rou ... more
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