US 22 (WV) Travel Info
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U.S. Route 22 (US 22) is a west–east route and is one of the original United States highways of 1926, running from Cincinnati, Ohio, at US 27, US 42, US 127, and US 52 to Newark, New Jersey, at U.S. Route 1/9 in the Newark Airport Interchange. US 22 also carries the names of the William Penn Highway throughout most of Pennsylvania. In southwest Ohio, it overl ... more
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